What does this research mean for the field?

Papillary muscles from hypertrophied rat hearts develop significantly greater maximum tension per unit weight compared to normal ventricles, under both oxygenated and anaerobic conditions. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1961Circulation Research

Tension Developed by Papillary Muscles from Hypertrophied Rat Hearts

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Population

Papillary muscle strips from hypertrophied left ventricles of 17 rats

Comparison

Electrical stimulation in a perfused… vs Papillary muscles from normal ventricles

Design

Preclinical

Authors

AKAndrew KerrCardiac Imaging AWAlan R. WinterbergerBuffalo VA Medical Center MGMARY GIAMBATTISTASUNY Upstate Medical University

Discussion

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Implication

Preclinical data show greater tension in hypertrophied rat ventricles; leaves open relevance to human heart failure.

Structured PICO

Population

Papillary muscle strips from hypertrophied left ventricles of 17 rats

Intervention

Electrical stimulation in a perfused, oxygenated, isometric muscle chamber (and with anaerobic perfusate)

Comparator

Papillary muscles from normal ventricles

Outcome

Maximum tension developed per unit weightsurrogate

Papillary muscles from hypertrophied rat hearts develop significantly greater maximum tension per unit weight than those from normal hearts.

Cite This Study

Kerr et al. (1961) studied this question.

synapsesocial.com/papers/6a15768ab2e0231f15828693 https://doi.org/10.1161/01.res.9.1.103

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Tension Developed by Papillary Muscles from Hypertrophied Rat Hearts

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Tension Developed by Papillary Muscles from Hypertrophied Rat Hearts

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider