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Virtually all recognized adverse drug reactions result in discontinuation or dose reduction of the suspected drug. In a study of adverse drug reactions, a pharmacist‐based surveillance system was used to monitor changes in drug orders. Drug reactions prompted 7.3 per cent of drug discontinuations or dose reductions. Compared with a physician‐based system of daily monitoring, the pharmacist‐based system detected more drug reactions, provided a more uniform method of study, and had greater acceptance by house physicians. Among 939 patients studied on the medical service of a university hospital, 48 (5.1 per cent) had adverse drug reactions on admission, and 99 (10.5 per cent) developed adverse drug reactions in the hospital.
Gardner et al. (Sun,) studied this question.