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December 1, 1997Journal of Internal Medicine

Major haemorrhagic complications during oral anticoagulant therapy in a Danish Population‐based cohort

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Population

682 consecutive out-patients commencing oral anticoagulant therapy in the County of North Jutland, Denmark

Design

Cohort

Follow-up

756 treatment-years of follow-up

Authors

FSFlemming Hald SteffensenLillebaelt HospitalKKKurt KristensenAarhus UniversityEEEjler EjlersenUniversity of Southern Denmark

Discussion

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Implication

Major bleeding during oral anticoagulation may exceed trial rates in community settings; challenges prior estimates and leaves open enhanced monitoring needs.

Structured PICO

P
Population
682 consecutive out-patients commencing oral anticoagulant therapy in the County of North Jutland, Denmark
I
Intervention
Oral anticoagulant therapy
O
Outcome
Fatal bleeding or bleeding demanding hospital admissionsafety

The rate of major bleeding during oral anticoagulant therapy in a routine community setting is higher than typically reported in randomized trials or specialist clinics.

Cite This Study

Steffensen et al. (1997) studied this question.

synapsesocial.com/papers/6a15867f79ff98d0de4ec28dhttps://doi.org/10.1111/j.1365-2796.1997.tb00023.x

Topics

Anticoagulation in AF
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk Factors for Complications of Chronic Anticoagulation: A Multicenter Study1993 · 674 citations
  2. 2Haemorrhagic and thromboembolic complications in patients with atrial fibrillation on anticoagulant prophylaxis1989 · 66 citations
  3. 3ABC of Atrial Fibrillation: ANTITHROMBOTIC TREATMENT FOR ATRIAL FIBRILLATION1996 · 77 citations
  4. 4The Pharmacoepidemiologic Prescription Database of North Jutland – a valid tool in pharmacoepidemiological research1997 · 89 citations
  5. 5Quality of oral anticoagulant control and treatment in Sweden1994 · 22 citations