Key result
Higher ALBI score predicts ~56% lower absolute long-term survival in elderly decompensated heart failure.
Why the study?
Risk stratification in elderly patients with HF is difficult and reliable tools for assessing mortality risk in this population are lacking.
Does the albumin-bilirubin (ALBI) score predict long-term mortality in elderly patients hospitalized for decompensated heart failure?
Cohort (n=242)
No
Does the albumin-bilirubin (ALBI) score predict long-term mortality in elderly patients hospitalized for decompensated heart failure?
Absolute Event Rate: 25.2% vs 81.1%
p-value: p=<0.001
The ALBI score is a strong prognostic tool for predicting long-term mortality in elderly patients hospitalized with decompensated heart failure.
ALBI may aid risk stratification in elderly decompensated HF; leaves open need for prospective validation before clinical adoption.
Background/Objective: Risk stratification in elderly patients with heart failure (HF) is very difficult. There is a lack of reliable tools for assessing the risk of death in this population of patients. The aim of this study was to determine the association between albumin–bilirubin (ALBI) score and long-term mortality in hospitalized elderly patients with decompensated HF. Methods: The study included 242 consecutive HF patients aged over 65 years hospitalized for worsening chronic HF at our institution between 2019 and 2023. The ALBI score was calculated according to the appropriate formula. Results: The median (IQR) age of the study population was 68.00 (range 66.0 to 74.6) years and 21.1% were female. The mean follow-up time was 352 ± 293 days. During the follow-up period, 47.1% patients died. The ALBI score generated good prognostic power (area under the curve = 0.822, p < 0.01) and specificity (86%) as well as acceptable sensitivity (68%) when predicting long-term mortality. Patients with higher ALBI scores (≥−2.191) had significantly worse long-term survival than patients with lower ALBI scores (<−2.191) [37 (25.2%) vs. 77 (81.1%); log rank p < 0.001]. Conclusions: This is the first study demonstrating that ALBI score has good prognostic power and allows for the successful prediction of mortality during long-term follow-up in the analyzed cohort.
No takes yet. Share an insight, caveat, or question.
Jurkiewicz et al. (2025) conducted a cohort in Decompensated Heart Failure (n=242). Albumin-Bilirubin (ALBI) score vs. Lower ALBI score (<-2.191) was evaluated on Long-term survival (p=<0.001). A higher ALBI score (≥−2.191) predicted significantly worse long-term survival compared to a lower score (25.2% vs. 81.1%; p<0.001) in elderly patients with decompensated heart failure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: