Why the study?
Does adding parenteral cephalothin sodium to oral neomycin and erythromycin reduce septic complication rates in patients undergoing large-bowel surgery?
Population
1,128 patients undergoing large-bowel surgery in a cooperative Veterans Administration study
Comparison
Oral neomycin and erythromycin base plus… vs Oral neomycin and erythromycin base plus…
Design
Other
Authors
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Adding parenteral antibiotics was not associated with lower septic rates; leaves open optimal prophylaxis regimens for elective colon surgery.
Does adding parenteral cephalothin sodium to oral neomycin and erythromycin reduce septic complication rates in patients undergoing large-bowel surgery?
Adding parenteral cephalothin to oral neomycin and erythromycin does not significantly reduce septic complications in elective colon surgery.
Robert E. Condon (1983) studied this question.
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