Population
8 patients 1 year after cardiac transplantation (2 of whom were studied again at 2 years)
Design
Case_series
Follow-up
1 and 2 years post-transplantation
Authors
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Supports exercise tolerance post-transplant; leaves open generalizability beyond this single case.
The transplanted human heart utilizes atypical adaptive mechanisms characteristic of denervation but responds appropriately to the metabolic demands of exercise 1 and 2 years postoperatively.
Stinson et al. (1972) studied this question.
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