Key result
CHA2DS2-VASc score weakly predicts recurrence in non-AF stroke survivors with an AUC of ~0.60.
Why the study?
Does the CHA2DS2-VASc score predict stroke recurrence in first-ever ischemic stroke survivors without atrial fibrillation?
Cohort (n=768)
No
Does the CHA2DS2-VASc score predict stroke recurrence in first-ever ischemic stroke survivors without atrial fibrillation?
The CHA2DS2-VASc score has limited predictive value for long-term stroke recurrence in patients without atrial fibrillation, highlighting the need for better risk stratification tools in this population.
CHA2DS2-VASc has limited predictive value for recurrence without AF; leaves open need for superior stratification tools.
OBJECTIVE: -VASc score in predicting stroke recurrence in first-ever ischemic stroke survivors without atrial fibrillation (AF). METHODS: - VASc score in predicting the risk of stroke recurrence in patients at different time points during the follow-up. The score has a better prediction ability for long-term stroke recurrence, but the prediction value remains low, suggesting the need to further improve the score or establish a new score for predicting stroke recurrence.
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Yang et al. (2020) conducted a cohort in First-ever ischemic stroke without atrial fibrillation (n=768). CHA2DS2-VASc score was evaluated on Prediction of 5-year stroke recurrence risk (AUC) (AUC 0.604, 95% CI 0.548-0.661, p=<0.001). The CHA2DS2-VASc score predicted the 5-year risk of stroke recurrence in first-ever ischemic stroke survivors without atrial fibrillation with an AUC of 0.604, indicating a low but significant predictive value.
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