Key result
ATRIA, CHADS2, and CHA2DS2-VASc stroke risk scores varied in relative performance based on population stroke rates, indicating cut-points may need optimization to fit local populations.
Why the study?
How do the ATRIA, CHADS2, and CHA2DS2-VASc stroke risk scores compare in predicting ischaemic stroke in a Swedish cohort of patients with atrial fibrillation?
How do the ATRIA, CHADS2, and CHA2DS2-VASc stroke risk scores compare in predicting ischaemic stroke in a Swedish cohort of patients with atrial fibrillation?
The relative performance of stroke risk scores in atrial fibrillation varies by population stroke rates, suggesting that score cut-points may need to be optimized locally.
AIMS: -VASc scores in a national Swedish AF (SAF) cohort. METHODS AND RESULTS: -VASc. Net reclassification improvement decreased when cut-points were altered to better fit the cohort's stroke rates. CONCLUSION: -VASc. However, relative performance of the categorical scores varied by population stroke rates. Score cut-points may need to be optimized to better fit local population stroke rates.
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Aspberg et al. (2016) studied this question. ATRIA, CHADS2, and CHA2DS2-VASc stroke risk scores varied in relative performance based on population stroke rates, indicating cut-points may need optimization to fit local populations.
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