Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2025Texas Heart Institute JournalOpen Access

Compared with a CHA2DS2-VASc score of 0 or 1, the hazard ratio of MACE occurrence was 3.22 (95% CI, 1.93-5.37; P < .01) for a score >2 and 1.92 (95% CI, 1.24-2.98; P < .01) for a score of 2.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

A research gap exists in applying the prognostic value of the CHA2DS2-VASc scoring system to patients with stroke who do not have atrial fibrillation.

Does a higher CHA2DS2-VASc score predict major adverse cardiac events in patients with acute ischemic stroke without atrial fibrillation?

Population

993 patients with acute ischemic stroke without AF

Comparison

High-risk (score >2) vs moderate-risk (score 2) vs low-risk (score 0-1) CHA2DS2-VASc groups

Design

Observational cohort study

Follow-up

1 year

Authors

MSMing-Juan SongXCXu Chen

Discussion

Loading...

Member takes

Overview

Supports closer surveillance of high-score non-AF AIS patients; leaves open whether CHA2DS2-VASc should influence secondary prevention.

Structured PICO

Does a higher CHA2DS2-VASc score predict major adverse cardiac events in patients with acute ischemic stroke without atrial fibrillation?

P
Population
993 patients with acute ischemic stroke (AIS) without atrial fibrillation (AF)
I
Intervention
High (CHA2DS2-VASc score >2, n=424) or moderate (CHA2DS2-VASc score 2, n=218) risk score
C
Comparator
Low risk score (CHA2DS2-VASc score 0-1, n=351)
O
Outcome
Major adverse cardiac events (MACE) at 1 year after index AIScomposite

The CHA2DS2-VASc score effectively stratifies the 1-year risk of major adverse cardiac events in patients with acute ischemic stroke who do not have atrial fibrillation.

Cite This Study

Song et al. (2025) studied this question.

synapsesocial.com/papers/6a7fdbae6670b810f4d2ea54https://doi.org/10.14503/thij-24-8450
View Full Paper
Ask AI
Bookmark
Share