Key result
Pulmonary vein isolation significantly improved left ventricular ejection fraction from 41% to 51% (P=0.004) at 6 months in patients with paroxysmal atrial fibrillation and baseline LVEF <50%.
Why the study?
Does pulmonary vein isolation improve cardiac function in patients with paroxysmal atrial fibrillation and impaired LVEF?
Cohort (n=70)
Does pulmonary vein isolation improve cardiac function in patients with paroxysmal atrial fibrillation and impaired LVEF?
Absolute Event Rate: 51% vs 41%
p-value: p=0.004
Pulmonary vein isolation significantly improves left ventricular ejection fraction in patients with paroxysmal atrial fibrillation and impaired baseline cardiac function.
Authors
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Supports considering PVI for LVEF recovery in paroxysmal AF with reduced function; leaves open randomized confirmation.
Lutomsky et al. (2008) conducted a cohort in Paroxysmal atrial fibrillation (n=70). Pulmonary vein isolation (PVI) vs. Baseline (pre-ablation) was evaluated on Left ventricular ejection fraction (LVEF) (p=0.004). Pulmonary vein isolation significantly improved left ventricular ejection fraction from 41% to 51% (P=0.004) at 6 months in patients with paroxysmal atrial fibrillation and baseline LVEF <50%.
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