Key result
Progressive anterior ablation in the coronary sinus region eliminated slow pathway tissue in 45% of patients and caused nonspecific AV node damage in 32%, with complete AV block induced in 23%.
Why the study?
What is the electrophysiological effect of progressive anterior ablation in the coronary sinus region on the AV node in patients with medically refractory paroxysmal atrial fibrillation?
Observational (n=22)
What is the electrophysiological effect of progressive anterior ablation in the coronary sinus region on the AV node in patients with medically refractory paroxysmal atrial fibrillation?
AV node modification for atrial fibrillation rate control appears to work via elimination of slow pathway tissue in about half of patients and nonspecific injury in others, though complete AV block occurs in a minority.
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Caution for complete AV block risk with anterior CS ablation; case report leaves open safe targeting for AV node modification in refractory AF.
Krahn et al. (1997) conducted an observational in Medically refractory paroxysmal atrial fibrillation (n=22). Progressive anterior ablation in the coronary sinus region was evaluated on Effect of progressive posteroseptal ablation on the AV node antegrade refractory curve. Progressive anterior ablation in the coronary sinus region eliminated slow pathway tissue in 45% of patients and caused nonspecific AV node damage in 32%, with complete AV block induced in 23%.
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