Key result
The spatiotemporal stability index of complex fractionated atrial electrograms decreased significantly prior to atrial fibrillation termination (p<0.001) and increased during sustained episodes.
Why the study?
Does the spatiotemporal stability of CFAE and DF correlate with AF sustenance and termination in a hypertensive sheep model?
Does the spatiotemporal stability of CFAE and DF correlate with AF sustenance and termination in a hypertensive sheep model?
p-value: p=<0.001
Spatiotemporal stabilization of complex fractionated atrial electrograms favors AF sustenance, while its destabilization heralds AF termination in a sheep model.
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CFAE spatiotemporal stability may mark AF sustenance in hypertensive sheep; leaves open translation to human mechanisms or ablation targets.
Thanigaimani et al. (2016) studied Atrial fibrillation (n=18). Spatiotemporal stability index (STSI) of CFAE was evaluated on Spatiotemporal stability index (STSI) of CFE-m prior to AF termination (p=<0.001). The spatiotemporal stability index of complex fractionated atrial electrograms decreased significantly prior to atrial fibrillation termination (p<0.001) and increased during sustained episodes.
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