Key result
This review highlights the pathophysiology of systemic right ventricular failure and recent developments in therapeutic research to facilitate clinical decision making.
Why the study?
What are the therapeutic options for systemic right ventricular failure compared to left ventricular failure?
What are the therapeutic options for systemic right ventricular failure compared to left ventricular failure?
This review summarizes the pathophysiology and therapeutic options for systemic right ventricular failure, highlighting differences from left ventricular failure management.
May inform decisions in systemic RV failure distinct from LV strategies; leaves open need for dedicated prospective trials.
The number of adult patients with a systemic right ventricle (RV) is steadily increasing. Survival is relatively good in these patients, but deterioration of the systemic RV seems inevitable. Although therapeutic options for patients with LV failure are well established, their role in patients with systemic RV failure is often undefined. To appreciate the potency of LV failure therapy in patients with a systemic RV, insight into pathophysiology of systemic RV failure and into recent developments in therapeutic research are indispensible. This review provides these insights, and will facilitate and ameliorate therapeutic decision making in patients with a systemic RV.
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Winter et al. (2008) conducted a review in Systemic right ventricular failure. Therapeutic options for systemic right ventricular failure vs. Left ventricular failure therapy was evaluated. This review highlights the pathophysiology of systemic right ventricular failure and recent developments in therapeutic research to facilitate clinical decision making.
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