Why the study?
Does large infarct size (measured by peak CK) increase the risk of stroke in patients with acute myocardial infarction?
Population
783 patients with acute myocardial infarction
Comparison
Large infarct size vs Smaller infarct size (peak CK < 1160 IU/l)
Design
Cohort
Authors
Loading...
Large infarct size by peak CK was associated with higher post-AMI stroke risk; leaves open whether anticoagulation benefits smaller infarcts.
Does large infarct size (measured by peak CK) increase the risk of stroke in patients with acute myocardial infarction?
The risk of stroke following acute myocardial infarction is highly dependent on infarct size, suggesting that routine anticoagulant prophylaxis may not be necessary for the majority of patients with smaller infarcts.
Thompson et al. (1978) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: