What question did this study set out to answer?

To sequence and assemble the complex 17-gigabase hexaploid genome of bread wheat and assess its gene content, structural dynamics, and evolution relative to ancestral diploid progenitors.

November 1, 2012NatureOpen Access

Analysis of the bread wheat genome using whole-genome shotgun sequencing

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Authors

RBRachel BrenchleyUniversity of Liverpool MSM. SpannaglJohn Innes Centre MPMatthias PfeiferLeibniz University Hannover

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Implication

Whole-genome sequencing reveals dynamic gene loss and metabolic gene family expansions in hexaploid bread wheat, highlighting key genetic mechanisms underlying crop productivity.

Key Points

To sequence and assemble the complex 17-gigabase hexaploid genome of bread wheat and assess its gene content, structural dynamics, and evolution relative to ancestral diploid progenitors.
Sequenced the 17-gigabase hexaploid genome of Triticum aestivum using whole-genome 454 pyrosequencing.
Compared assembly data against ancestral and progenitor diploid cereal genomes using high-resolution synteny mapping.
Identified between 94,000 and 96,000 genes, assigning two-thirds across the A, B, and D component subgenomes.
Demonstrated marked structural dynamics characterized by extensive loss of gene family members upon polyploidization and domestication, alongside widespread gene fragments.
Identified targeted expansions in gene families responsible for energy harvesting, metabolism, and growth that correlate with crop productivity.

Cite This Study

Brenchley et al. (2012) studied this question.

synapsesocial.com/papers/6a15a2e4d64fa333899fe5aa https://doi.org/10.1038/nature11650

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Implication

Whole-genome sequencing reveals dynamic gene loss and metabolic gene family expansions in hexaploid bread wheat, highlighting key genetic mechanisms underlying crop productivity.

Analysis of the bread wheat genome using whole-genome shotgun sequencing

Discussion

Member takes

Implication

Key Points

Cite This Study

Analysis of the bread wheat genome using whole-genome shotgun sequencing

Discussion

Member takes

Implication

Key Points

Cite This Study

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