Key result
Middle septal cardiac pacing resulted in a significantly shorter QRS complex duration (153.89 ms) compared to apical (179.94 ms), low septal (172.56 ms), and RVOT (171.66 ms) stimulation (p<0.001).
Why the study?
Ventricular pacing impairs cardiac function, particularly with apical pacing widening the QRS complex, leaving the optimal cardiac pacing site uncertain.
Does middle septal cardiac stimulation reduce QRS complex duration compared to apical, low septal, or RVOT stimulation in patients with pacemakers?
Population
323 pacemaker patients at Monte Sinai Hospital in Cuenca-Ecuador
Comparison
Apical vs low septal vs middle septal vs RVOT stimulation
Design
Retrospective observational study
Authors
Loading...
Middle septal pacing was associated with shorter QRS duration; leaves open whether this improves clinical outcomes versus other right ventricular sites.
Observational (n=323)
No
Does middle septal cardiac stimulation reduce QRS complex duration compared to apical, low septal, or RVOT stimulation in patients with pacemakers?
Absolute Event Rate: 153.89% vs 179.94%
p-value: p=<0.001
Middle septal pacing results in significantly shorter QRS duration compared to apical, low septal, or RVOT pacing, suggesting better synchronization of myocardial contraction.
Coello et al. (2020) conducted an observational in Pacemaker implantation (n=323). Middle septal cardiac stimulation vs. Apical, low septal, and right ventricular outflow tract stimulation was evaluated on Duration of stimulated QRS complexes (p=<0.001). Middle septal cardiac pacing resulted in a significantly shorter QRS complex duration (153.89 ms) compared to apical (179.94 ms), low septal (172.56 ms), and RVOT (171.66 ms) stimulation (p<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: