What question did this study set out to answer?

To evaluate the association between noninvasively diagnosed large-vessel and small-vessel peripheral arterial disease and subsequent mortality in older adults.

October 1, 1985Circulation

Noninvasively diagnosed peripheral arterial disease as a predictor of mortality: results from a prospective study.

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To evaluate the association between noninvasively diagnosed large-vessel and small-vessel peripheral arterial disease and subsequent mortality in older adults.
Prospective cohort study evaluating 567 older subjects from a defined population followed for an average of 4 years.
Participants underwent noninvasive vascular testing to evaluate large-vessel and small-vessel peripheral arterial disease alongside assessments of intermittent claudication and peripheral pulses.
Large-vessel peripheral arterial disease significantly predicted all-cause mortality in men and women (relative risk: 4 to 5), remaining independent of other cardiovascular risk factors and baseline cardiovascular disease.
Associations of intermittent claudication and abnormal peripheral pulses with mortality were weaker than large-vessel disease, while isolated small-vessel peripheral arterial disease was not associated with mortality.

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Implication

Prospective cohort study shows large-vessel peripheral arterial disease quadruples all-cause mortality risk in older adults, highlighting the prognostic utility of noninvasive vascular testing.

Cite This Study

Criqui et al. (1985) studied this question.

synapsesocial.com/papers/6a15b81f79ff98d0de4f085f https://doi.org/10.1161/01.cir.72.4.768

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Implication

Prospective cohort study shows large-vessel peripheral arterial disease quadruples all-cause mortality risk in older adults, highlighting the prognostic utility of noninvasive vascular testing.

Noninvasively diagnosed peripheral arterial disease as a predictor of mortality: results from a prospective study.

Key Points

Discussion

Implication

Cite This Study

Noninvasively diagnosed peripheral arterial disease as a predictor of mortality: results from a prospective study.

Key Points

Discussion

Implication

Cite This Study

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