Key result
Intermittent claudication in men was associated with a substantially increased risk of death (OR 3.8; 95% CI 2.2 to 6.5) after standardization for age and smoking.
Why the study?
What is the prevalence, incidence, and mortality risk associated with intermittent claudication in middle-aged men?
Population
All men aged 45 to 59 registered with 16 general practitioners in the general population.
Design
Cohort
Follow-up
11 years
Authors
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Intermittent claudication signals high mortality risk in men; hypothesis-generating and requires prospective validation before guiding practice.
Cohort
What is the prevalence, incidence, and mortality risk associated with intermittent claudication in middle-aged men?
Effect estimate: OR 3.8 (95% CI 2.2 to 6.5)
Intermittent claudication is a strong indicator of high mortality risk, primarily from circulatory causes, and is strongly associated with smoking and ischemic heart disease.
Bainton et al. (1994) conducted a cohort in Intermittent claudication. Intermittent claudication vs. Without intermittent claudication was evaluated on Death (OR 3.8, 95% CI 2.2 to 6.5). Intermittent claudication in men was associated with a substantially increased risk of death (OR 3.8; 95% CI 2.2 to 6.5) after standardization for age and smoking.
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