Key result
Among survivors of myocardial infarction, intermittent claudication was associated with an increased risk of death or nonfatal cardiac events (38.5% vs 17.8%, P=.001).
Why the study?
Does the presence of intermittent claudication predict recurrent cardiac events and mortality in survivors of myocardial infarction?
Population
1045 survivors of myocardial infarction assessed 2 months after index MI
Comparison
Presence of intermittent claudication vs Absence of intermittent claudication
Design
Cohort
Follow-up
mean 26 months
Authors
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Intermittent claudication may identify higher-risk post-MI survivors; leaves open whether targeted interventions improve outcomes.
Cohort (n=1,045)
Does the presence of intermittent claudication predict recurrent cardiac events and mortality in survivors of myocardial infarction?
Absolute Event Rate: 38.5% vs 17.8%
p-value: p=.001
Intermittent claudication in post-MI patients is a strong independent predictor of recurrent cardiovascular events and mortality, associated with heightened inflammation and underuse of beta-blockers.
Craig R. Narins (2004) conducted a cohort in Myocardial Infarction (n=1,045). Intermittent claudication vs. No intermittent claudication was evaluated on combined end point of death or nonfatal cardiac event (p=.001). Among survivors of myocardial infarction, intermittent claudication was associated with an increased risk of death or nonfatal cardiac events (38.5% vs 17.8%, P=.001).
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