Key result
Free-breathing 3D viability MRI at 3.0 T was successfully achieved in 84% of patients (21/25) and showed excellent agreement with 2D imaging for transmural extension of myocardial damage (k=0.91).
Why the study?
Does free-breathing high-spatial-resolution delayed contrast-enhanced 3D viability MRI at 3.0T improve the assessment of myocardial damage compared to breath-hold 2D viability imaging in patients with myocardial diseases?
Observational (n=25)
Does free-breathing high-spatial-resolution delayed contrast-enhanced 3D viability MRI at 3.0T improve the assessment of myocardial damage compared to breath-hold 2D viability imaging in patients with myocardial diseases?
Free-breathing high-spatial-resolution delayed contrast-enhanced 3D viability MRI at 3.0 T is feasible and comparable to 2D imaging for evaluating myocardial damage.
PURPOSE: To assess the feasibility of free-breathing high-spatial-resolution delayed contrast-enhanced three-dimensional (3D) viability magnetic resonance imaging (MRI) at 3.0 T for the detection of myocardial damages. MATERIALS AND METHODS: Twenty-five patients with myocardial diseases, including myocardial infarction and cardiomyopathies, were enrolled after informed consent was given. Free-breathing 3D viability MRI with high spatial resolution (1.5 x 1.25 x 2.5 mm) at 3.0 T, for which cardiac and navigator gating techniques were employed, was compared with breath-hold two-dimensional (2D) viability imaging (1.77 x 1.18 x 10 mm) for assessment of contrast-to-noise ratio (CNR) and myocardial damage. RESULTS: Free-breathing 3D viability imaging was achieved successfully in 21 of the 25 patients. This imaging technique depicted 84.6% of hyperenhancing myocardium with a higher CNR between hyperenhancing myocardium and blood and with excellent agreement for the transmural extension of myocardial damage (k = 0.91). In particular, the 3D viability images delineated the myocardial infarction and linear hyperenhancing myocardium, comparable to the 2D viability images. CONCLUSION: Free-breathing high-spatial-resolution delayed contrast-enhanced 3D viability MRI using 3.0 T was feasible for the evaluation of hyperenhancing myocardium, as seen with myocardial infarction and cardiomyopathies.
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Amano et al. (2008) conducted an observational in Myocardial diseases (myocardial infarction and cardiomyopathies) (n=25). Free-breathing 3D viability MRI at 3.0 T vs. Breath-hold 2D viability imaging was evaluated on Contrast-to-noise ratio (CNR) and myocardial damage (k = 0.91). Free-breathing 3D viability MRI at 3.0 T was successfully achieved in 84% of patients (21/25) and showed excellent agreement with 2D imaging for transmural extension of myocardial damage (k=0.91).
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