Key result
Diabetes mellitus in patients with heart failure was associated with an 8-fold higher overall mortality rate in men and a 5.5-fold higher mortality rate in women compared to those without diabetes.
Why the study?
This study aimed to analyze all-cause mortality in patients with heart failure with and without diabetes mellitus in Poland in 2012 using national health and insurance registers.
Does diabetes mellitus increase all-cause mortality in patients with heart failure?
Observational (n=201,586)
Yes
Does diabetes mellitus increase all-cause mortality in patients with heart failure?
Effect estimate: 8-fold higher (men), 5.5-fold higher (women)
Diabetes mellitus is associated with a substantially higher mortality rate in patients with heart failure, particularly in men.
May warrant closer surveillance of HF patients with diabetes; leaves open causal mechanisms and intervention effects.
BACKGROUND This retrospective study aimed to analyze all-cause mortality in patients with heart failure with and without diabetes mellitus in 2012 in Poland using data from the National Health Fund [Narodowy Fundusz Zdrowia] (NFZ), the Central Register of the Insured [Centralna Baza Ubezpieczonych] (CBU), and the Polish Universal Electronic System for Registration of the Population (PESEL). MATERIAL AND METHODS Between 1st January 2012 and 31st December 2012, data were analyzed from the NFZ, CBU, and PESEL to include all patients with a primary diagnosis of heart failure, with and without diabetes mellitus and all-cause mortality data. Structured Query Language (SQL) was used to retrieve and manage data from NFZ, CBU, and PESEL. RESULTS In Poland, 32.58% of 201,586 patients with a primary diagnosis of heart failure who died in 2012 also had a diagnosis of diabetes mellitus. The overall mortality rate in men with heart failure and diabetes was eight times higher than for men with heart failure without diabetes. The overall mortality rate in women with diabetes and heart failure was 5.5 times higher compared with women with heart failure without diabetes. More than 90% of deaths in female patients with heart failure, with or without diabetes, occurred in women >60 years. For male patients with heart failure with or without diabetes, 70% of deaths occurred in men >60 years. CONCLUSIONS These findings support the need for continued prevention programs, early diagnosis, and treatment of diabetes, and highlight the increase in mortality for patients with heart failure and diabetes.
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Wierzba et al. (2019) conducted an observational in Heart failure (n=201,586). Diabetes mellitus vs. No diabetes mellitus was evaluated on All-cause mortality (8-fold higher (men), 5.5-fold higher (women)). Diabetes mellitus in patients with heart failure was associated with an 8-fold higher overall mortality rate in men and a 5.5-fold higher mortality rate in women compared to those without diabetes.
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