Key result
MicroRNAs regulate AF remodeling and circulating levels show potential as non-invasive biomarkers.
Why the study?
Pathophysiological mechanisms underlying AF development remain incompletely understood, and optimal biomarkers for early detection and prognosis are lacking.
Understanding the specific microRNAs involved in atrial fibrillation pathophysiology may lead to the development of novel targeted therapies and non-invasive diagnostic biomarkers.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for microRNA biomarkers in AF; leaves open clinical translation pending prospective validation.
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Chaulin et al. (2020) conducted a review in Atrial Fibrillation. MicroRNAs was evaluated. MicroRNAs play a leading role in the pathophysiology of atrial fibrillation by regulating mechanisms of atrial remodeling, and circulating microRNAs show potential as non-invasive biomarkers.
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