Key result
Endurance and high-intensity intermittent training increase the capacity for maximal exercise vasodilatation by 20-30%, whereas this capacity is blunted with aging and in chronic heart failure.
Sympathetic restraint of exercise-induced vasodilatation is critical for maintaining blood pressure during maximal exercise, especially in patients with limited cardiac pumping capacity such as those with heart failure.
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May inform exercise prescriptions in HF and aging; leaves open optimal protocols via prospective trials.
Calbet et al. (2012) conducted a review in Health, aging, chronic heart failure, and chronic hypoxia. Endurance and high-intensity intermittent training was evaluated. Endurance and high-intensity intermittent training increase the capacity for maximal exercise vasodilatation by 20-30%, whereas this capacity is blunted with aging and in chronic heart failure.
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