Key result
Presence of myocardial scar was associated with significantly lower left atrial ejection fraction (45.9% vs 51.3%) and higher minimum left atrial volume compared to matched controls.
Why the study?
Is left atrial function associated with left ventricular myocardial fibrosis in a multi-ethnic population?
Population
429 participants from a multi-ethnic population identified from 2839 participants who had undergone cardiac…
Design
Case-control
Authors
Loading...
LA impairment linked to scar merits prospective validation; leaves open causality and utility for risk stratification.
Case-Control (n=429)
Yes
Is left atrial function associated with left ventricular myocardial fibrosis in a multi-ethnic population?
Absolute Event Rate: 45.9% vs 51.3%
p-value: p=<0.001
Reduced left atrial regional and global function are significantly associated with both replacement and diffuse left ventricular myocardial fibrosis.
Imai et al. (2014) conducted a case-control in Myocardial fibrosis (n=429). Myocardial scar (determined by late gadolinium enhancement) vs. Matched controls without myocardial scar was evaluated on Left atrial ejection fraction (LA EF) (p=<0.001). Presence of myocardial scar was associated with significantly lower left atrial ejection fraction (45.9% vs 51.3%) and higher minimum left atrial volume compared to matched controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: