Why the study?
Does balloon angioplasty cause persistent dysfunction of regenerated endothelium in rabbit iliac arteries?
Population
47 New Zealand White rabbits
Comparison
Balloon angioplasty in the left iliac artery vs Control (contralateral) uninjured iliac arteries
Design
Preclinical
Follow-up
2 and 4 weeks
Authors
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Animal data link injury severity to endothelial dysfunction; leaves open human relevance and therapeutic implications.
Does balloon angioplasty cause persistent dysfunction of regenerated endothelium in rabbit iliac arteries?
Balloon angioplasty induces persistent endothelial dysfunction in regenerated cells, the duration and severity of which depend on the initial injury and correlate with intimal thickening.
Weidinger et al. (1990) studied this question.
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