What question did this study set out to answer?

Provide comprehensive rationales, operational details, and published examples for the 21 items of the revised ARRIVE 2019 guidelines to improve the reporting transparency and reproducibility of animal experiments.

July 15, 2019Open Access

Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019

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Authors

NSNathalie Percie du SertNational Centre for the Replacement Refinement and Reduction of Animals in Research AAAmrita AhluwaliaVascular Medicine SASabina AlamBioMed Central (United Kingdom)

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Implication

Methodological guidance establishes standardized reporting practices in animal research, indicating actionable pathways to enhance reproducibility across biomedical science.

Key Points

Provide comprehensive rationales, operational details, and published examples for the 21 items of the revised ARRIVE 2019 guidelines to improve the reporting transparency and reproducibility of animal experiments.
Updated the original 2010 ARRIVE guidelines through an international revision initiative to overcome implementation barriers.
Developed an Explanation and Elaboration framework compiling evidence-based rationales and published examples for all 21 checklist items.
Presents an updated 21-item consensus checklist defining the minimum reporting standards necessary to evaluate and reproduce in vivo scientific studies.
Outlines practical examples and contextual guidance to assist authors, peer reviewers, and journal editors in operationalizing transparent reporting.

Cite This Study

Sert et al. (2019) studied this question.

synapsesocial.com/papers/6a15e5d812229ed7d8d12d4d https://doi.org/10.1101/703355

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Implication

Methodological guidance establishes standardized reporting practices in animal research, indicating actionable pathways to enhance reproducibility across biomedical science.

Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019

Discussion

Member takes

Implication

Key Points

Cite This Study

Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019

Discussion

Member takes

Implication

Key Points

Cite This Study

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