What question did this study set out to answer?

To estimate the incidence rates of dementia, Alzheimer's disease, and vascular dementia in an elderly community-dwelling population.

January 1, 1994International Journal of Epidemiology

Incidence of Dementia and Alzheimer's Disease in Elderly Community Residents of South-Western France

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Authors

LLLuc LetenneurUniversité de Bordeaux DCDaniel CommengesBordeaux Population Health JDJ.F. DartiguesUniversité de Bordeaux

Discussion

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Implication

Cohort study reveals rising dementia and Alzheimer disease incidence with advancing age in community-dwelling older adults, highlighting lifetime neurodegenerative risks.

Key Points

To estimate the incidence rates of dementia, Alzheimer's disease, and vascular dementia in an elderly community-dwelling population.
Prospective cohort study of N=2,792 community residents evaluated at baseline, 1-year, and 3-year follow-up intervals.
Cases were identified via a two-step diagnostic procedure combining psychologist-administered screening using DSM-IIIR criteria followed by neurological evaluation applying NINCDS-ADRDA criteria.
Annual incidence was estimated at 16.3 per 1,000 person-years for dementia overall and 11.4 per 1,000 person-years for Alzheimer's disease.
Incidence increased steeply across age groups, rising from 2.0 per 1,000 (ages 65–69) to 74.0 per 1,000 (ages >90) for dementia, and from 0.7 per 1,000 to 66.0 per 1,000 for Alzheimer's disease.
Disease incidence did not plateau in advanced age and showed no significant difference between men and women.

Cite This Study

Letenneur et al. (1994) studied this question.

synapsesocial.com/papers/6a15ee5bbdb7c25666523eac https://doi.org/10.1093/ije/23.6.1256

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January 1, 1994International Journal of Epidemiology

Incidence of Dementia and Alzheimer's Disease in Elderly Community Residents of South-Western France

View Full Paper

Ask AI

Bookmark

Authors

LLLuc LetenneurUniversité de Bordeaux DCDaniel CommengesBordeaux Population Health JDJ.F. DartiguesUniversité de Bordeaux

Discussion

Member takes

Implication

Cohort study reveals rising dementia and Alzheimer disease incidence with advancing age in community-dwelling older adults, highlighting lifetime neurodegenerative risks.

Key Points

To estimate the incidence rates of dementia, Alzheimer's disease, and vascular dementia in an elderly community-dwelling population.
Prospective cohort study of N=2,792 community residents evaluated at baseline, 1-year, and 3-year follow-up intervals.
Cases were identified via a two-step diagnostic procedure combining psychologist-administered screening using DSM-IIIR criteria followed by neurological evaluation applying NINCDS-ADRDA criteria.
Annual incidence was estimated at 16.3 per 1,000 person-years for dementia overall and 11.4 per 1,000 person-years for Alzheimer's disease.
Incidence increased steeply across age groups, rising from 2.0 per 1,000 (ages 65–69) to 74.0 per 1,000 (ages >90) for dementia, and from 0.7 per 1,000 to 66.0 per 1,000 for Alzheimer's disease.
Disease incidence did not plateau in advanced age and showed no significant difference between men and women.

Cite This Study

Letenneur et al. (1994) studied this question.

synapsesocial.com/papers/6a15ee5bbdb7c25666523eac https://doi.org/10.1093/ije/23.6.1256

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