Key result
A new class of deformable models using MRI-SPAMM was developed to quantitatively analyze and visualize left ventricular epicardial, endocardial, and mid-wall motion.
A novel class of deformable models using MRI-SPAMM data enables detailed 3-D quantitative analysis of left ventricular wall motion.
Advances quantitative LV motion analysis in research; leaves open clinical adoption pending validation.
We have developed a new class of deformable models suitable for analyzing the left ventricular shape and motion. The models allow us to estimate the deformation and complex motion of the left ventricle (LV) in terms of a few global parameter functions whose values are allowed to vary locally. Using Lagrangian dynamics and the finite element theory, we convert these volumetric primitives into models that deform due to forces exerted by the data points. We present experiments where we used magnetic tagging (MRI-SPAMM) to acquire datapoints from the LV during systole. By plotting the variations over time of the extracted LV model parameters we quantitatively analyze, localize and compare the epicardial and endocardial motion. We also present mid-wall motion analysis results from healthy volunteers and patients with hypertrophic cardiomyopathy.
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Park et al. (2002) studied Hypertrophic cardiomyopathy. Deformable models with parameter functions (MRI-SPAMM) was evaluated. A new class of deformable models using MRI-SPAMM was developed to quantitatively analyze and visualize left ventricular epicardial, endocardial, and mid-wall motion.
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