Key result
Female sex in aortic stenosis is associated with concentric left ventricular hypertrophy and appears to confer a survival advantage following transcatheter aortic valve replacement.
Why the study?
How do sex differences impact left ventricular remodeling and clinical outcomes following surgical or transcatheter aortic valve replacement in patients with aortic stenosis?
Population
Patients with aortic stenosis
Comparison
Surgical aortic valve replacement and… vs Male vs female sex
Design
Review
Authors
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May inform sex-specific TAVR counseling; leaves open prospective validation of survival differences.
How do sex differences impact left ventricular remodeling and clinical outcomes following surgical or transcatheter aortic valve replacement in patients with aortic stenosis?
This review highlights that women with aortic stenosis develop different patterns of left ventricular remodeling compared to men and may have better survival outcomes following TAVR but worse outcomes following SAVR.
Dobson et al. (2015) conducted a review in Aortic stenosis. Surgical and Transcatheter Aortic Valve Replacement (SAVR and TAVR) vs. Male vs Female sex was evaluated. Female sex in aortic stenosis is associated with concentric left ventricular hypertrophy and appears to confer a survival advantage following transcatheter aortic valve replacement.
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