Key result
Normal adult aging up to the eighth decade was not significantly correlated with changes in left ventricular isovolumic relaxation time constants (Tb: r = .001 to .10, P = NS; Tw: r = .02 to .05, P = NS).
Why the study?
Does aging alter left ventricular isovolumic relaxation in normal human subjects?
Population
55 normal subjects who underwent diagnostic cardiac catheterization but were found to have normal cardiac…
Design
Cross-sectional
Authors
Loading...
LV isovolumic relaxation remains stable with normal aging; challenges animal data and leaves open other contributors to diastolic changes.
Observational (n=55)
Does aging alter left ventricular isovolumic relaxation in normal human subjects?
Effect estimate: Tb: r = .001 to .10; Tw: r = .02 to .05
p-value: p=NS
In humans with normal cardiac anatomy and function, left ventricular isovolumic relaxation remains essentially unchanged with normal adult aging up to the eighth decade.
Yamakado et al. (1997) conducted an observational in Normal cardiac anatomy and function (n=55). Aging was evaluated on Left ventricular isovolumic relaxation assessed by exponential time constants of isovolumic pressure decay (Tb and Tw) (Tb: r = .001 to .10; Tw: r = .02 to .05, p=NS). Normal adult aging up to the eighth decade was not significantly correlated with changes in left ventricular isovolumic relaxation time constants (Tb: r = .001 to .10, P = NS; Tw: r = .02 to .05, P = NS).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: