Key result
The concept of cardiac L-type calcium channel regulation via signal transduction processes and cAMP-dependent phosphorylation has become more elaborate over the past decade.
Provides a comprehensive review of the signal transduction and phosphorylation mechanisms regulating cardiac L-type calcium channels.
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Highlights growing complexity of L-type Ca channel regulation; leaves open targeted mechanistic studies before clinical translation.
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Trautwein et al. (1990) conducted a review in Cardiac L-Type Calcium Current regulation. The concept of cardiac L-type calcium channel regulation via signal transduction processes and cAMP-dependent phosphorylation has become more elaborate over the past decade.
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