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July 1, 2015Revista Brasileira de Cardiologia Invasiva (English Edition)Open Access

Percutaneous occlusion of the left atrial appendage with AMPLATZER® Cardiac Plug for the prevention of thromboembolic events in chronic atrial fibrillation

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Why the study?

Does percutaneous occlusion of the left atrial appendage with AMPLATZER Cardiac Plug provide safe and effective closure in patients with atrial fibrillation and contraindications to oral anticoagulation?

Population

13 patients with permanent or paroxysmal atrial fibrillation and contraindications or complications of oral…

Design

Case_series

Follow-up

mean 12.2 months

Key result

Left atrial appendage occlusion using the AMPLATZER Cardiac Plug was safe and effective, with 100% of appendages remaining closed at a mean follow-up of 12.2 months.

Authors

FCFrancisco ChamiéÊGÊnio Eduardo GuériosVFValério Fuks

Discussion

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Member takes

Overview

May be considered in select anticoagulation-intolerant AF cases; leaves open questions on comparative effectiveness and generalizability.

Study Design

Type

Observational (n=13)

Structured PICO

Does percutaneous occlusion of the left atrial appendage with AMPLATZER Cardiac Plug provide safe and effective closure in patients with atrial fibrillation and contraindications to oral anticoagulation?

P
Population
13 patients with permanent (84.6%) or paroxysmal atrial fibrillation and contraindications or complications of oral anticoagulation, mean age 66.7 years, 5 males and 8 females. Included patients had LAA anatomy compatible with the occluder and no thrombi.
I
Intervention
Percutaneous occlusion of the left atrial appendage with AMPLATZER Cardiac Plug
O
Outcome
Safety and efficacy (LAA closure, residual defect, death)

LAA occlusion using the AMPLATZER Cardiac Plug is a safe and effective alternative to oral anticoagulation in selected patients with atrial fibrillation.

Limitations

  • Small series of patients
  • small series of patients

Cite This Study

Chamié et al. (2015) conducted an observational in Atrial fibrillation (n=13). AMPLATZER Cardiac Plug was evaluated on LAA closure and safety. Left atrial appendage occlusion using the AMPLATZER Cardiac Plug was safe and effective, with 100% of appendages remaining closed at a mean follow-up of 12.2 months.

synapsesocial.com/papers/6a16022b7cdde9fcee12759ahttps://doi.org/10.1016/j.rbciev.2015.08.002
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