Key result
Left atrial appendage occlusion using the AMPLATZER Cardiac Plug in high-risk NVAF patients was associated with a 95.5% procedural success rate and an annual ischaemic stroke rate of 0.8%.
Why the study?
Does percutaneous left atrial appendage occlusion prevent ischaemic stroke in high-risk patients with non-valvular atrial fibrillation and contraindications to oral anticoagulation?
Cohort (n=134)
Does percutaneous left atrial appendage occlusion prevent ischaemic stroke in high-risk patients with non-valvular atrial fibrillation and contraindications to oral anticoagulation?
LAAO with the AMPLATZER Cardiac Plug provides effective long-term stroke prevention with low complication rates in high-risk NVAF patients contraindicated for oral anticoagulation.
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Supports LAAO feasibility with ACP in high-risk NVAF; leaves open randomized confirmation of long-term stroke prevention.
Santoro et al. (2016) conducted a cohort in non-valvular atrial fibrillation (n=134). Percutaneous left atrial appendage occlusion (LAAO) using the AMPLATZER Cardiac Plug (ACP) was evaluated on Ischaemic stroke (annual rate). Left atrial appendage occlusion using the AMPLATZER Cardiac Plug in high-risk NVAF patients was associated with a 95.5% procedural success rate and an annual ischaemic stroke rate of 0.8%.
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