Key result
Shallow septal myectomy plus MV repair relieves LVOTO and MR without excess arrhythmias versus extended Morrow.
Why the study?
Outcomes of transaortic shallow septal myectomy with MV repair compared to extended Morrow procedure in treating HOCM with severe interstitial fibrosis were lacking.
Does transaortic shallow septal myectomy concomitant with mitral valvuloplasty improve LVOTO and MR compared to the extended Morrow procedure in patients with HOCM and severe interstitial fibrosis?
Cohort (n=36)
No
Does transaortic shallow septal myectomy concomitant with mitral valvuloplasty improve LVOTO and MR compared to the extended Morrow procedure in patients with HOCM and severe interstitial fibrosis?
Transaortic shallow septal myectomy combined with mitral valve repair is an effective alternative to the extended Morrow procedure for relieving LVOTO and MR in HOCM patients with severe interstitial fibrosis and intrinsic mitral valve abnormalities.
May support shallow myectomy plus mitral repair in fibrotic HOCM; hypothesis-generating and requires randomized confirmation before practice change.
Background: There is lack of outcomes of transaortic shallow septal myectomy with mitral valve(MV) repair comparing with extended Morrow procedure in treatment of hypertrophic obstructive cardiomyopathy (HOCM) with severe interstitial fibrosis.
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Lei Yan (2023) conducted a cohort in Hypertrophic Obstructive Cardiomyopathy (HOCM) (n=36). Transaortic shallow septal myectomy with mitral valvuloplasty (MVP) vs. Extended Morrow procedure was evaluated on Reduction in left ventricular outflow tract pressure gradient (LVOT PG) and mitral regurgitation. Transaortic shallow septal myectomy combined with mitral valve repair effectively relieved left ventricular outflow tract obstruction and decreased mitral regurgitation without increasing postoperative arrhythmias compared to the extended Morrow procedure.
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