Key result
Modified Morrow septal myectomy resulted in a greater reduction in left ventricular outflow tract gradient compared to the classic procedure.
Why the study?
Does modified Morrow septal myectomy improve echocardiographic parameters and symptoms compared to classic Morrow septal myectomy in patients with hypertrophic obstructive cardiomyopathy?
Observational (n=42)
No
Does modified Morrow septal myectomy improve echocardiographic parameters and symptoms compared to classic Morrow septal myectomy in patients with hypertrophic obstructive cardiomyopathy?
Modified Morrow septal myectomy provides superior reduction in LV outflow tract gradient and velocity compared to the classic procedure in patients with hypertrophic obstructive cardiomyopathy.
Answers are grounded in this paper and cite their sources.
May favor modified Morrow myectomy in obstructive HCM; hypothesis-generating and requires prospective validation before practice change.
This study aimed to compare the efficacy and safety of the classic Morrow septal myectomy with the modified procedure in treating hypertrophic obstructive cardiomyopathy (HOCM).A retrospective study was conducted to compare the outcomes of classic with modified Morrow septal myectomy in 42 patients treated from January 2005 to July 2011. Preoperative and postoperative ventricular septal thickness, left ventricular (LV) outflow tract velocity and gradient were measured echocardiographically.In both groups, the ventricular septal thickness, LV outflow tract velocity, and LV outflow tract gradient were significantly decreased after the operation. The modified Morrow procedure group, however, showed significantly greater reduction in these echocardiographic parameters than the classic procedure group. All patients in the modified procedure group were asymptomatic postoperatively with a postoperative transvalvular pressure gradient <30 mm Hg. In the classic procedure group, only 14 (87.5%) patients, however, were asymptomatic postoperatively with a postoperative transvalvular pressure gradient <30 mm Hg, and 2 patients still had severe LV outflow obstruction postoperatively.The modified Morrow septal myectomy is safe and effective in treating HOCM patients, and is superior to the classic procedure in reducing the LV outflow tract gradient and velocity, restoring normal anatomic atrioventricular size, and alleviating symptoms associated with HOCM.
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Song et al. (2016) conducted an observational in Hypertrophic obstructive cardiomyopathy (n=42). Modified Morrow septal myectomy vs. Classic Morrow septal myectomy was evaluated on Reduction in left ventricular outflow tract gradient (mm Hg) (p=<0.001). Modified Morrow septal myectomy resulted in a greater reduction in left ventricular outflow tract gradient compared to the classic procedure.
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