Key result
Adding MV surgery to the Morrow procedure is linked to ~78% lower LVOT gradients and resolved SAM.
Why the study?
Indications for a concomitant mitral valve procedure to relieve mitral regurgitation or intrinsic mitral valve pathological changes during a modified Morrow procedure for HOCM remain controversial.
Does concomitant mitral valve surgery during a modified Morrow procedure safely and effectively improve hemodynamics in patients with hypertrophic obstructive cardiomyopathy?
Observational (n=56)
No
Does concomitant mitral valve surgery during a modified Morrow procedure safely and effectively improve hemodynamics in patients with hypertrophic obstructive cardiomyopathy?
Concomitant mitral valve surgery during a modified Morrow procedure is safe and effectively relieves left ventricular outflow tract obstruction and mitral regurgitation in patients with HOCM.
Concomitant MV surgery may be feasible in select HOCM myectomy cases; leaves open optimal indications versus myectomy alone.
Ventricular septal myectomy (modified Morrow procedure) is the gold standard surgical intervention for hypertrophic obstructive cardiomyopathy (HOCM). However, the indications for a concomitant mitral valve (MV) procedure to relieve mitral regurgitation (MR) or intrinsic MV pathological changes remain controversial. We aimed to retrospectively analyze this series of patients to evaluate the safety and efficiency of the procedure at our center.We retrospectively reviewed a total of 56 consecutive patients with HOCM who underwent concomitant MV surgery with modified Morrow procedures at our center between January 2019 and December 2021. The baseline characteristics, perioperative data, and postoperative outcomes were examined.The operative mortality rate was 0% among all 56 patients. Two patients had complete atrioventricular block, two patients experienced renal failure, and one patient required reoperation for bleeding. The peak gradient of the left ventricular outflow tract decreased from 93.6 ± 34.4 mm Hg to 20.5 ± 13.0 mm Hg. MR was significantly relieved, and the systolic anterior motion of the MV resolved completely after concomitant MV surgery. During a mean follow-up of 13.8 ± 7.1 months, no patient required cardiac reoperation.Concomitant surgery of the MV during the modified Morrow procedure was performed safely and effectively in the treatment of most types of HOCM in our practice.
No takes yet. Share an insight, caveat, or question.
Liang et al. (2025) conducted an observational in Hypertrophic Obstructive Cardiomyopathy (n=56). Concomitant mitral valve surgery with modified Morrow procedure vs. Preoperative baseline was evaluated on Peak left ventricular outflow tract (LVOT) gradient (p=<0.001). Concomitant mitral valve surgery during the modified Morrow procedure safely reduced the mean peak left ventricular outflow tract gradient from 93.6 mm Hg to 20.5 mm Hg and completely resolved systolic anterior motion.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: