Key result
Concomitant mitral valve surgery during the modified Morrow procedure did not significantly impact 6-month postoperative KCCQ scores compared to the isolated procedure in patients with HOCM.
Why the study?
The study investigated the impact of the modified Morrow procedure, with or without concomitant mitral valve surgery, on KCCQ scores and quality of life in patients with HOCM.
Does concomitant mitral valve surgery impact KCCQ scores in HOCM patients undergoing the modified Morrow procedure compared to the isolated procedure?
Observational (n=82)
No
Does concomitant mitral valve surgery impact KCCQ scores in HOCM patients undergoing the modified Morrow procedure compared to the isolated procedure?
Concomitant mitral valve surgery during the modified Morrow procedure for HOCM does not negatively impact postoperative quality of life compared to the isolated procedure, as both yield similar significant improvements in KCCQ scores.
Should not yet alter perioperative strategies for modified Morrow in HOCM; leaves open value of adding mitral valve surgery pending RCTs.
Background: This study aimed to investigate the impact of the modified Morrow procedure, with or without concomitant mitral valve surgery, on Kansas City Cardiomyopathy Questionnaire (KCCQ) scores and quality of life (QoL) in patients with hypertrophic obstructive cardiomyopathy (HOCM), and to provide an evidence base for the development of perioperative management strategies. Methods: A retrospective analysis was conducted on 82 patients with HOCM who underwent the modified Morrow procedure. Patients were divided into two groups: those who received the modified Morrow procedure alone (n = 41) and those who underwent the combined procedure (n = 41). Baseline characteristics, postoperative follow-up parameters, and changes in KCCQ scores were compared between the two groups. Results: The two groups were comparable at baseline, except for a significant difference in preoperative mitral regurgitation (p < 0.05). No significant differences were observed between the groups in postoperative KCCQ scores or cardiac function parameters (p > 0.05). Repeated-measures analysis of variance revealed a significant main effect of time (p < 0.001), but no significant main effect of surgical group or time-by-group interaction (p > 0.05). Conclusion: The modified Morrow procedure significantly improves QoL in patients with HOCM. Concomitant mitral valve surgery does not impose an additional burden on KCCQ scores. Clinical efforts should focus on meticulous perioperative management throughout the care cycle and on personalized cardiac rehabilitation guidance to facilitate postoperative recovery. Ultimately, these measures support a closed-loop “assessment–intervention–monitoring–follow-up” management system that continuously safeguards the QoL and the long-term prognosis of patients undergoing the combined procedure.
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Li et al. (2026) conducted an observational in Hypertrophic obstructive cardiomyopathy (HOCM) (n=82). Modified Morrow procedure combined with mitral valve surgery vs. Isolated modified Morrow procedure was evaluated on Kansas City Cardiomyopathy Questionnaire (KCCQ) score at 6 months postoperatively (p=0.842). Concomitant mitral valve surgery during the modified Morrow procedure did not significantly impact 6-month postoperative KCCQ scores compared to the isolated procedure in patients with HOCM.
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