Key result
Moderate-to-severe MR does not impact 3-year event-free survival after extended Morrow without mitral valve intervention.
Why the study?
The indications for a concomitant mitral valve procedure remain controversial for patients with hypertrophic obstructive cardiomyopathy undergoing extended Morrow procedures.
Does an extended Morrow procedure without a concomitant mitral valve procedure result in similar event-free survival in HOCM patients with moderate to severe preoperative MR compared to those with mild MR?
Population
232 consecutive HOCM patients undergoing extended Morrow procedures from January 2010 to October 2014
Comparison
Preoperative mild MR versus moderate or severe MR
Design
Retrospective cohort study
Authors
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May support omitting mitral intervention for SAM-related moderate-severe MR in HOCM; leaves open randomized confirmation.
Cohort (n=232)
No
Does an extended Morrow procedure without a concomitant mitral valve procedure result in similar event-free survival in HOCM patients with moderate to severe preoperative MR compared to those with mild MR?
Absolute Event Rate: 88% vs 89.6%
p-value: p=0.820
Concomitant mitral valve procedures are not necessary for HOCM patients undergoing an extended Morrow procedure when mitral regurgitation is caused by systolic anterior motion, even if moderate to severe.
Liu et al. (2016) conducted a cohort in Hypertrophic obstructive cardiomyopathy (n=232). Preoperative moderate or severe mitral regurgitation vs. Preoperative mild mitral regurgitation was evaluated on 3-year composite end-point event-free survival (p=0.820). Preoperative moderate to severe mitral regurgitation did not significantly impact 3-year composite event-free survival compared to mild mitral regurgitation in patients undergoing an extended Morrow procedure without mitral valve intervention (88.0% vs 89.6%, p=0.820).
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