September 15, 2015Interactive Cardiovascular and Thoracic SurgeryOpen Access

The surgical management of hypertrophic obstructive cardiomyopathy with the concomitant mitral valve abnormalities

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Why the study?

Does ventricular septal myotomy-myectomy with or without concomitant mitral valve procedures improve LVOT gradient and symptoms in patients with HOCM and mitral valve abnormalities?

Population

76 patients with hypertrophic obstructive cardiomyopathy and concomitant mitral valve abnormalities, mean…

Design

Cohort

Follow-up

5-18 years

Authors

BCBin CuiChina Pharmaceutical University SWShuiyun WangCardiac Surgery JXJianping XuChinese Academy of Medical Sciences & Peking Union Medical College

Discussion

Member takes

Implication

Supports myectomy in HOCM with mitral issues; observational data leaves open need for RCTs before practice change.

Structured PICO

Does ventricular septal myotomy-myectomy with or without concomitant mitral valve procedures improve LVOT gradient and symptoms in patients with HOCM and mitral valve abnormalities?

Population

76 patients with hypertrophic obstructive cardiomyopathy (HOCM) and concomitant mitral valve abnormalities, mean age 37.18 ± 15.85 years, 51 males and 25 females. All had left ventricular outflow tract (LVOT) obstruction with a resting or physically provoked gradient of ≥50 mmHg and systolic anterior movement (SAM) of the mitral leaflets, and 64 had mitral regurgitation (MR).

Intervention

Ventricular septal myotomy-myectomy under general anaesthesia and cardiopulmonary bypass, with concomitant mitral valve replacement (n=14) or mitral valve plasty (n=12) as needed.

Outcome

Reduction in resting LVOT gradient and mean septal thickness, improvement in mitral regurgitation and SAM, and hospital mortality.surrogate

Ventricular septal myotomy-myectomy, with concomitant mitral valve procedures when necessary, effectively reduces LVOT gradient and improves symptoms in patients with HOCM and mitral valve abnormalities.

Cite This Study

Cui et al. (2015) studied this question.

synapsesocial.com/papers/6a821bee757d76b9faa20c12 https://doi.org/10.1093/icvts/ivv257

Topics

Mitral valve intervention Valvular heart disease Hypertrophic cardiomyopathy

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The surgical management of hypertrophic obstructive cardiomyopathy with the concomitant mitral valve abnormalities

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

The surgical management of hypertrophic obstructive cardiomyopathy with the concomitant mitral valve abnormalities

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider