Key Points
- The study aims to evaluate how left ventricular volume and mass relate to function in patients with severe coronary artery disease.
- Studied 23 patients using coronary arteriography and biplane angiocardiography.
- Measured end-diastolic volumes, left ventricular mass, and ejection fraction.
- Analyzed the association of mitral regurgitant volume with left ventricular volume.
- End-diastolic volume ranged from 55 to 317 ml/m², with mass ranging from 83 to 294 g/m².
- Significant correlation observed: increased end-diastolic volume associated with increased mass (r = 0.77, P < 0.01).
- Mitral regurgitant volume was observed in 15 patients, with end-diastolic volumes greater than 154 ml/m² linked to regurgitation.
Structured PICO
PPopulation23 patients with severe coronary artery disease and refractory angina pectoris or persistent congestive heart failure, or both. 15 had clinical and electrocardiographic evidence of previous myocardial infarction.
OOutcomeLeft ventricular chamber volume, mass, and function (including ejection fraction and mitral regurgitation)surrogate
In patients with severe coronary artery disease, left ventricular dilatation is proportional to hypertrophy and frequently associated with mitral regurgitation, reflecting reduced left ventricular performance.