Key result
Aspirin remains a cornerstone of antiplatelet therapy, though ongoing debates include optimal dosing, primary prevention thresholds, gender differences, resistance, and novel chemopreventive uses.
This review summarizes the current understanding of aspirin's molecular mechanisms, clinical efficacy, and ongoing debates regarding its optimal use in cardiovascular prevention.
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Aspirin use warrants individualized assessment amid debates; leaves open optimal dosing and prevention thresholds for prospective trials.
Patrono et al. (2008) conducted a review in Cardiovascular disease prevention. Aspirin was evaluated. Aspirin remains a cornerstone of antiplatelet therapy, though ongoing debates include optimal dosing, primary prevention thresholds, gender differences, resistance, and novel chemopreventive uses.
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