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January 1, 1982Japanese Circulation JournalOpen Access

Cineangiographic evaluation of diastolic properties of the left ventricle in man.

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Population

110 patients with various heart diseases

Design

Cross-sectional

Authors

HTHaruo TomodaYOYASUAKI OOEDARTRyusuke Tagawa

Discussion

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Overview

Myocardial stiffness associated with delayed relaxation in LVH; hypothesis-generating for calcium antagonists, needs prospective confirmation before practice change.

Structured PICO

P
Population
110 patients with various heart diseases (19 normal cases, 13 mitral stenosis, 19 left ventricular volume overload, 18 coronary artery diseases without myocardial infarction, 27 myocardial infarction, 6 hypertrophic cardiomyopathy, 5 congestive cardiomyopathy and 3 chronic constrictive pericarditis)
I
Intervention
Cineangiographic evaluation of diastolic properties; calcium antagonist administration in a subset of patients with left ventricular hypertrophy
O
Outcome
Diastolic properties including diastolic maximal circumferential relaxation velocity (maxVcf), diastolic maximal dV/dt, volume change during early 1/3 of ventricular filling (V1/3), rapid filling time, isovolumic relaxation time, and myocardial stiffness constant Ksurrogate

Cineangiographic evaluation demonstrates that increased myocardial stiffness correlates with prolonged isovolumic relaxation time, and calcium antagonists may improve delayed relaxation in hypertrophied hearts.

Cite This Study

Tomoda et al. (1982) studied this question.

synapsesocial.com/papers/6a160a6c0d802d0924b560dchttps://doi.org/10.1253/jcj.46.64
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