Key result
An intraoperative fall in systolic blood pressure >50% from baseline for >5 minutes was associated with a more than doubled risk of postoperative acute kidney injury (OR 2.46).
Why the study?
Does intraoperative hypotension increase the risk of acute kidney injury in adult patients undergoing major elective noncardiac surgery?
Population
470 adult patients undergoing major elective noncardiac surgery scheduled for an overnight admission in the…
Comparison
Intraoperative hypotension vs Absence of intraoperative hypotension or lesser…
Design
Cohort
Follow-up
first two postoperative days (up to 30 days for mortality)
Authors
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May warrant closer intraoperative BP monitoring in noncardiac surgery; extends observational links to AKI but leaves causality and intervention effects open.
Cohort (n=470)
No
Does intraoperative hypotension increase the risk of acute kidney injury in adult patients undergoing major elective noncardiac surgery?
Effect estimate: OR 2.46 (95% CI 1.31-4.62)
In patients undergoing major noncardiac surgery, intraoperative hypotension (SBP decrease >50% from baseline) is independently associated with a more than doubled risk of acute kidney injury.
Hallqvist et al. (2017) conducted a cohort in Major elective non-cardiac surgery (n=470). Intraoperative hypotensive event >50% decrease in systolic blood pressure vs. ≤40% decrease in systolic blood pressure was evaluated on Postoperative acute kidney injury (AKI) (OR 2.46, 95% CI 1.31-4.62). An intraoperative fall in systolic blood pressure >50% from baseline for >5 minutes was associated with a more than doubled risk of postoperative acute kidney injury (OR 2.46).
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