Key result
Intraoperative hypotension during non-cardiac surgery was associated with increased risks of postoperative morbidity (OR 2.08; 95% CI 1.56-2.77) and mortality (OR 1.94; 95% CI 1.32-2.84).
Why the study?
Intraoperative hypotension has varying definitions in the literature and may be associated with postoperative complications.
Does intraoperative hypotension increase postoperative morbidity and mortality in patients undergoing non-cardiac surgery?
Meta-Analysis (n=130,862)
Does intraoperative hypotension increase postoperative morbidity and mortality in patients undergoing non-cardiac surgery?
Odds Ratio: 2.08 (95% CI 1.56–2.77)
Intraoperative hypotension during non-cardiac surgery is significantly associated with increased postoperative morbidity, mortality, cardiac complications, and acute kidney injury.
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May warrant closer hemodynamic monitoring in non-cardiac surgery; leaves open whether targeted interventions reduce events.
Wijnberge et al. (2021) conducted a meta-analysis in non-cardiac surgery (n=130,862). Intraoperative hypotension vs. No intraoperative hypotension was evaluated on postoperative overall morbidity (OR 2.08, 95% CI 1.56-2.77). Intraoperative hypotension during non-cardiac surgery was associated with increased risks of postoperative morbidity (OR 2.08; 95% CI 1.56-2.77) and mortality (OR 1.94; 95% CI 1.32-2.84).
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