Key result
Cardiac resynchronization therapy via biventricular pacing provides important clinical benefits for patients with advanced systolic dysfunction and left bundle branch block.
Why the study?
Does cardiac resynchronization therapy (biventricular pacing) improve clinical outcomes in highly symptomatic patients with advanced systolic dysfunction and left bundle branch block?
Does cardiac resynchronization therapy (biventricular pacing) improve clinical outcomes in highly symptomatic patients with advanced systolic dysfunction and left bundle branch block?
Cardiac resynchronization therapy via biventricular pacing, combined with an ICD, provides important clinical benefits for highly symptomatic patients with advanced systolic dysfunction and LBBB.
May support CRT decisions in advanced HF with LBBB; leaves open need for updated RCTs amid evolving medical therapy.
Despite medical therapy, many patients with advanced systolic dysfunction remain highly symptomatic. In these patients the presence of a left bundle branch block on electrocardiogram indicates significant dyssynchrony of ventricular contraction. Cardiac resynchronization, by means of biventricular pacing, results in important clinical benefits. Due to the risk for malignant ventricular arrhythmias, this technology is best combined with an implantable cardioverter defibrillator.
No takes yet. Share an insight, caveat, or question.
Peter Ott (2005) conducted a review in Advanced Congestive Heart Failure. Cardiac resynchronization therapy (biventricular pacing) with implantable cardioverter defibrillator was evaluated. Cardiac resynchronization therapy via biventricular pacing provides important clinical benefits for patients with advanced systolic dysfunction and left bundle branch block.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: