Key result
Prevalence of a urinary Na/K ratio ≥2 among Koreans reaches 72% by 2023.
Why the study?
Japanese guidelines recommend urinary sodium-to-potassium ratio cutoffs of 2 and 4 to assess hypertension and cardiovascular risk, but the proportion of Koreans classified as elevated by these thresholds was unknown.
Cross-Sectional (n=50,440)
Yes
The prevalence of elevated urinary sodium-to-potassium ratios has significantly increased among Koreans from 2016 to 2023, highlighting a growing population-level cardiovascular risk factor.
Answers are grounded in this paper and cite their sources.
Rising Na/K ratios signal increasing population CV risk in Koreans; leaves open causal links and intervention effects.
Background/Objectives: Recent Japanese guidelines recommend using the average sodium-to-potassium (Na/K) ratio from casual urine samples to assess hypertension and cardiovascular risk, suggesting cutoffs of 2 (optimal) and 4 (feasible). We aimed to evaluate the proportion of Korean individuals who would be classified as having elevated Na/K ratios using these cutoffs, based on random urine Na/K measurements obtained from the nationally representative Korea National Health and Nutrition Examination Survey (KNHANES) dataset. Methods: We analyzed 50,440 participants from the KNHANES 2016–2023 with available random urine Na and K results. Annual urinary Na/K ratios were calculated, and the prevalence of ratios ≥2 and ≥4 was assessed by age and sex using sampling weights. Results: The weighted median Na/K ratios were consistently lower than the weighted means, indicating skewed distributions. From 2016 to 2023, the weighted median and mean values increased from 2.3 and 2.7 to 2.8 and 3.3, respectively. The prevalence of a Na/K ratio ≥2 increased from 60.5% to 72.0%, and that of a ratio ≥4 increased from 16.9% to 28.3%. A U-shaped trend in Na/K ≥4 prevalence was observed by age, highest among those <20 and ≥70 years. Males had a higher prevalence than females in all age groups except 20–29. Conclusions: A growing proportion of Koreans exceeded Na/K cutoffs of 2 and 4 over time. Age- and sex-specific variation suggests tailored interpretation may be necessary when applying these thresholds in population health monitoring.
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Choi et al. (2025) conducted a cross-sectional in Elevated urinary sodium-to-potassium ratio (n=50,440). Urinary sodium-to-potassium (Na/K) ratio assessment was evaluated on Prevalence of urinary Na/K ratios ≥2 and ≥4. The prevalence of a urinary Na/K ratio ≥2 increased from 60.5% to 72.0%, and a ratio ≥4 increased from 16.9% to 28.3% among Koreans from 2016 to 2023.
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