Key result
Cardiac MRI abnormalities were detected in 58.5% of patients with RVOT tachycardia compared to 6.7% of controls (P<0.001) and predicted unfavorable outcomes of radiofrequency ablation.
Why the study?
Do cardiac MRI abnormalities and SAECG late potentials predict the outcome of radiofrequency ablation in patients with RVOT tachycardia?
Case-Control (n=56)
Do cardiac MRI abnormalities and SAECG late potentials predict the outcome of radiofrequency ablation in patients with RVOT tachycardia?
Cardiac MRI abnormalities and SAECG late potentials are frequently found in patients with RVOT tachycardia and predict unfavorable outcomes following radiofrequency ablation.
Answers are grounded in this paper and cite their sources.
Cardiac MRI may identify RVOT tachycardia patients at higher ablation failure risk; leaves open whether imaging should guide selection pending prospective validation.
BACKGROUND: Recent reports have shown abnormalities on cardiac magnetic resonance imaging (MRI) in patients with right ventricular outflow tract (RVOT) tachycardia. OBJECTIVES: OBJECTIVES of this study were to demonstrate abnormalities on MRI and signal-averaged ECG (SAECG) in patients with RVOT tachycardia and their correlation with the outcome of radiofrequency (RF) ablation. METHODS: We studied 41 patients with symptomatic RVOT tachycardia and 15 controls. SAECG and cardiac MRI were performed on every subject. An evaluation of structural abnormality, chamber size, function, and wall motion abnormality of the left and right ventricle was performed by MRI. Focal wall thinning was evaluated by the black blood technique and fatty infiltration was evaluated by the T1 image with and without fat suppression. RESULTS: MRI abnormalities were demonstrated in 24 (58.5%) patients with RVOT tachycardia. The abnormalities included localized wall bulging in 22 (53.7%), focal wall thinning in 10 (24.4%), and fatty replacement in 9 (22%) patients. MRI abnormality was found in only one patient in the control group (P < 0.001). Late potentials from SAECG were demonstrated in six (10.7%) patients but none in the controls (P = 0.117). Among 29 patients who underwent RF ablation, 3 patients had a failed procedure and 3 having arrhythmia recurrence needed repeated ablation. MRI abnormalities and late potentials were associated with an unfavorable outcome of RF ablation. CONCLUSIONS: MRI abnormalities were frequently found in patients with RVOT tachycardia. MRI abnormalities and late potentials can predict outcomes of RF ablation.
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Krittayaphong et al. (2006) conducted a case-control in Right ventricular outflow tract (RVOT) tachycardia (n=56). Cardiac MRI and SAECG vs. Controls was evaluated on MRI abnormalities (p=<0.001). Cardiac MRI abnormalities were detected in 58.5% of patients with RVOT tachycardia compared to 6.7% of controls (P<0.001) and predicted unfavorable outcomes of radiofrequency ablation.
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