Key result
African American or black race was not associated with differences in ED treatment with diuretics (adjusted OR 1.00; 95% CI 0.55-1.82) or 30-day adverse events compared to white patients.
Why the study?
Is African American or black race associated with disparities in ED treatment or 30-day outcomes in patients with acute heart failure compared to white race?
Observational (n=418)
Yes
Is African American or black race associated with disparities in ED treatment or 30-day outcomes in patients with acute heart failure compared to white race?
Effect estimate: adjusted OR 1.00 (95% CI 0.55-1.82)
Supports equitable ED diuretic use and outcomes in acute HF across races; hypothesis-generating and requires prospective validation.
OBJECTIVES: It has been well documented that screening, prevention, and treatment disparities in cardiovascular care exist. Most studies have focused on the outpatient setting. The purpose of the present analysis was to assess if a disparity of care exists in the care of emergency department (ED) patients with acute heart failure in a secondary analysis of the Heart Failure and Audicor Technology for Rapid Diagnosis and Initial Treatment (HEARD-IT) multinational study. METHODS: Only patients with an adjudicated diagnosis of acute heart failure were included in this analysis. Racial groups included in this analysis were limited to white and African American or black patients, due to their predominance in the cohort. Logistic regression including clinically relevant demographics, past medical history, exam, diagnostic tests, and adjudicated diagnosis of acute heart failure as covariates was performed to assess the association of race with treatment with a diuretic or nitroglycerin and 30-day death or readmission. RESULTS: Of the cohort, 418 of 1,076 (38.8%) were included in the analysis. Median age was 69 years (interquartile range [IQR]=55-79 years), 49% were white, and 51% were African American or black. There was no difference in the correct admitting diagnosis in the two groups (p=0.83). Multivariate adjustment revealed that African American or black race was not associated with treatment with diuretics (adjusted odds ratio [OR]=1.00, 95% confidence interval [CI]=0.55 to 1.82) or nitrates (adjusted OR=1.27, 95% CI=0.76 to 2.13) in the ED. In a separate regression analysis there was no association with African American or black race with 30-day adverse events (adjusted OR=1.22, 95% CI=0.68 to 2.16). CONCLUSIONS: This secondary analysis of HEARD-IT data did not identify racial disparities in the treatment of adults with acute heart failure in the ED.
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Diercks et al. (2011) conducted an observational in Acute heart failure (n=418). African American or black race vs. White race was evaluated on Treatment with diuretics in the ED (adjusted OR 1.00, 95% CI 0.55-1.82). African American or black race was not associated with differences in ED treatment with diuretics (adjusted OR 1.00; 95% CI 0.55-1.82) or 30-day adverse events compared to white patients.
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