Key result
Culture-negative mitral valve endocarditis occurred in a previously asymptomatic woman with hypertrophic cardiomyopathy, resulting in death.
Case Report (n=1)
This case report of fatal infective endocarditis in a patient with hypertrophic obstructive cardiomyopathy questions the current guideline stance against routine antibiotic prophylaxis in this population.
Questions guidelines against prophylaxis in HCM; single case report is hypothesis-generating.
Infective endocarditis is a relatively rare complication of hypertrophic cardiomyopathy. Infective endocarditis in hypertrophic cardiomyopathy is almost always seen in patients with outflow obstruction and is more common in those with both outflow obstruction and atrial dilatation. We present a case of culture negative mitral valve endocarditis in a previously asymptomatic woman with hypertrophic cardiomyopathy who died in the course of the disease.
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Güler et al. (2014) conducted a case report in Hypertrophic Obstructive Cardiomyopathy and Infective Endocarditis (n=1). Culture-negative mitral valve endocarditis occurred in a previously asymptomatic woman with hypertrophic cardiomyopathy, resulting in death.