Key result
Breast artery calcification correlates with coronary artery calcification in women over 40.
Why the study?
Breast artery calcification found routinely on mammography in elderly women could serve as a predictor of coronary artery calcification.
Does breast artery calcification predict coronary artery calcification in women over 40 with suspected coronary artery disease?
Cross-Sectional (n=60)
No
Does breast artery calcification predict coronary artery calcification in women over 40 with suspected coronary artery disease?
p-value: p=0.001
Breast artery calcification detected on routine mammography is significantly correlated with coronary artery calcification, suggesting it could serve as a useful predictor for cardiovascular disease risk.
May support opportunistic cardiovascular risk assessment via mammography in women over 40; leaves open prospective validation of incremental utility.
Introduction Coronary artery disease is the main cause of burden of disease in the world. Coronary calcification is seen as an aetiopathological event in the pathogenesis of cardiovascular diseases. Studies have shown that breast artery calcification, which is routinely found in mammography of elderly women, could be predictive of coronary artery calcification. Material and methods In this cross-sectional study, 60 women over 40 years of age were included. All of these patients had undergone mammography after having an indication to undergo a computed tomography-angiography. Breast arterial calcification and calcium scores were determined for each patient, and the paired-t test was used to analyse the data. Results The mean age of patients was 49.52 ± 8.83 years. Of these 60 women, 50% were postmenopausal and 50% were not. In 37 (61.7%) cases, mild to severe coronary calcification was observed, and 50 (83.3%) had mild to severe breast arterial calcification. There was a significant correlation between coronary calcification and breast artery calcification (p = 0.001), and there was also a significant relationship between coronary calcification and postmenopausal calcification (p < 0.001). Conclusions Breast artery calcification can be a suitable predictor for coronary artery calcification and is a valid method for predicting cardiovascular disease probability in the future.
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Seifi et al. (2020) conducted a cross-sectional in Coronary artery disease (n=60). Breast artery calcification was evaluated on Correlation between coronary calcification and breast artery calcification (p=0.001). Breast artery calcification was significantly correlated with coronary artery calcification (p = 0.001) in women over 40 years of age.
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